Recombinant Human TARC (CCL17)

• Description:

  Thymus and activation-regulated chemokine (TARC) is a recently identified CC chemokine that is expressed constitutively in the thymus and transiently in stimulated peripheral blood mononuclear cells. TARC functions as a selective chemoattractant for T cells that express a class of receptors binding TARC with high affinity and specificity. The chemokine TARC is a ligand for the chemokine receptor CCR4 expressed on CD4 Th2 cells.

• Gene Name:

  CCL17

• Gene Aliases:

  CC chemokine TARC, Small-inducible cytokine A17, C-C motif chemokine 17, chemokine 17, CCL17, ABCD-2, SCYA17, TARC
  Recombinant Human Thymus and Activation-Regulated Chemokine (CCL17)

• Gene ID:

  6361

• Accession Number:

  Q92583

• Organism:

  Human

• Source:

  E. coli

• Concentration:

  <1.0 EU/μg of recombinant protein as determined by the LAL method.

• Purity:

  >95% as determined by SDS-PAGE

• Solubility:

  A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

• Function:

  Determined by its ability to chemoattract human T cells using a concentration range of 2-40 ng/mL.

• Molecular Weight:

  8

• Shipping Conditions:

  Ambient Temperature

• Storage Conditions:

  The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

• Appearance:

  Lyophilized Powder

• Formulation:

  Lyophilized from a 0.2 μm filtered solution in PB,100 mM NaCl, pH 7.5.

• CAS Number:

  9000-83-3