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Nepaprazole

CAT: 0804-HY-19153Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19153Size:1 Each
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Description
Nepaprazole (rel-TY-11345 free base) is a proton pump inhibitor. Nepaprazole inhibits H+/K+-ATPase activity in isolated rabbit gastric mucosal microsomes with the IC50 values of 5.8 μM and 9.9 μM at pH 6.0 and pH 7.4, respectively. Nepaprazole can be used for study of peptic ulcer diseases[1].
CAS Number
156601-79-5
Product Name Alternative
Rel-TY-11345 (free base)
UNSPSC
12352005
Target
Proton Pump
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nepaprazole.html
Smiles
O=S(C1=NC2=CC=CC=C2N1)[C@@]3([H])C4=NC=CC(OC)=C4CCCC3
Molecular Formula
C18H19N3O2S
Molecular Weight
341.43
References & Citations
[1]Yamaguchi T, et al. Biochemical and pharmacological properties of a newly synthesized proton pump (H+/K (+) -ATPase) inhibitor, TY-11345 in experimental animals. Jpn J Pharmacol. 1993;62 (4) :363-371.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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