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Nepaprazole

CAT: 0931-T28156-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T28156-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
156601-79-5
Target
Others, Proton pump
Related Pathways
Others, Membrane transporter/Ion channel
Bioactivity
Nepaprazole is a proton pump inhibitor. TY-11345 potently inhibited H+/K (+) -ATPase activity in isolated rabbit gastric mucosal microsomes, and the inhibitory effect was enhanced under weak acid conditions, the IC50 being 5.8 microM and 9.9 microM at pH 6.0 and pH 7.4, respectively.
Smiles
S(=O)([C@]1(C=2C(=C(OC)C=CN2)CCCC1)[H])C=3NC=4C(N3)=CC=CC4
Molecular Formula
C18H19N3O2S
Molecular Weight
341.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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