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Nepaprazole sodium

CAT: 0931-T70428-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T70428-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
157564-11-9
Target
Others
Related Pathways
Others
Bioactivity
Nepaprazole Na is the salt form of Nepaprazole Free Base, also known as TY-11345, is a proton pump inhibitor potentially for treatment of gastric ulcer. TY-11345 potently inhibited H+/K (+) -ATPase activity in isolated rabbit gastric mucosal microsomes; and the inhibitory effect was enhanced under weak acid conditions, the IC50 (concentrations that inhibit the enzyme activity by 50%) being 5.8 microM and 9.9 microM at pH 6.0 and pH 7.4, respectively. TY-11345 should be useful for the clinical treatment of peptic ulcer diseases.
Smiles
[Na+].[H][C@]1(CCCCc2c(OC)ccnc12)S(=O)c1nc2ccccc2[n-]1
Molecular Formula
C18H18N3NaO2S
Molecular Weight
363.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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