Recombinant Human CTNNB1 Protein
CAT:
763-PDEH100744-02
Size:
20 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Human CTNNB1 Protein
- Background: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome.
- Abbreviation: CTNNB1
- Synonyms: Beta-catenin, CTNNB, Catenin beta-1, OK, PRO2286, SW-cl.35
- CAS Number: 9000-83-3
- UniProt: P35222
- Accession Number: P35222
- Host: E. coli
- Origin Species: Human
- Tag: N-His
- Sequence: Met131-Tyr670
- Field of Research: Cancer;Cardiovascular;Neuroscience;Signal Transduction
- Purity: > 85% as determined by reducing SDS-PAGE.
- Bioactivity: Not validated for activity
- Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
- Molecular Weight: 59 kDa
- Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
- Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.