Recombinant Human S100A9 Protein

• Background:

  Protein S100-A9 (also MRP14 and calgranulin B) is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response.It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism.

• Abbreviation:

  S100A9

• Synonyms:

  CAGB; CFAG; Calgranulin-B; Calprotectin L1H subunit; Leukocyte L1 complex heavy chain; MRP-14; Protein S100-A9

• Accession Number:

  P06702

• Expression System:

  E.coli

• Tag:

  None

• Sequence:

  Thr 2-Pro114

• Field of Research:

  Signal Transduction; Cell biology; Cancer; epigenetics and nuclear signal; immunology

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 95 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  13.2 kDa

• Observed Molecular Weight:

  14 kDa

• Species:

  Human