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Globomycin derivative G2A

CAT: 0804-HY-P10389Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P10389Size:1 Each
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Description
Globomycin derivative G2A (Compound G2A) is an inhibitor for lipoprotein signal peptidase II (LspA), with an IC50 of 604 nM. Globomycin derivative G2A inhibits E. coli, P. aeruginosa and A. baumannii, with MIC ranging from 12.5 to 32 μg/mL[1].
UNSPSC
12352209
Target
Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/globomycin-derivative-g2a.html
Solubility
10 mM in DMSO
Smiles
O=C(CCNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](N(C([C@@H]1C)=O)C)CC(C)C)=O)[C@@H](CC)C)=O)CO)=O)[C@@H](O)C)=O)N1CCCCCCCC
Molecular Formula
C34H62N6O8
Molecular Weight
682.89
References & Citations
[1]Craven TW, et al., Computational Design of Cyclic Peptide Inhibitors of a Bacterial Membrane Lipoprotein Peptidase. ACS Chem Biol. 2024 May 17;19 (5) :1125-1130.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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