ATG7 (3D6) Mouse mAb

• Background:

  The molecular machinery of autophagy was largely discovered in yeast and referred to as autophagy-related (Atg) genes. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.

• Description:

  The molecular machinery of autophagy was largely discovered in yeast and referred to as autophagy-related (Atg) genes. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.

• Synonyms:

  APG7, GSA7, Autophagy related protein 7

• Gene ID:

  10533

• UniProt:

  O95352

• Cellular Locus:

  Cytoplasm

• Host:

  Mouse

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant Protein

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Source:

  Mouse

• Applications:

  IHC

• Validated Applications:

  IHC

• Stability:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Concentration:

  1 mg/mL

• Dilution:

  IHC 1:100-200

• Molecular Weight:

  78kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  78 kDa

• Subcellular Location:

  Cytoplasm

• Other Product Names:

  APG7, GSA7, Autophagy related protein 7

• Gene ID (Human):

  10533

• SwissProt (Human):

  O95352