Anti-MUC2(MLP/842), CF594 conjugate

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Dry Ice Shipment: No

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Custom Services: We offer custom development, testing, and other tailored services for Anti-MUC2(MLP/842), CF594 conjugate to help researchers meet specific project requirements with precision.
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Anti-MUC2(MLP/842), CF594 conjugate

CAT:

37-BNC940842-100

Size:

100 µL

Anti-MUC2(MLP/842), CF594 conjugate

Description: Recognizes a single glycoprotein of 520 kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium.MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary._x000D__x000D_Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_
Synonyms: Mucin-2, Intestinal mucin-2, Mucin like protein, (MLP), SMUC
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MUC2
Gene ID: 4583
NCBI Gene ID: 315
UniProt: Q02817
Cellular Locus: Secreted (extracellular)
Host: Mouse
Species Reactivity: Human
Immunogen: Recombinant human MUC2 protein
Target Antigen: MUC2 | Mucin 2
Clonality: Monoclonal
Isotype: IgG1 κ
Clone: MLP/842
Conjugation: CF594
Disease: Tumor
Source: Animal
Applications: IHC, FFPE (verified)
Validated Applications: IHC, FFPE
Field of Research: Cancer, Mucins
Positive Control: LS174T cells or small intestine.
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 520 kDa
Additionnal Information: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunofluorescence: 1-2 ug/mL|Does not react with rat; others not known|Immunohistology formalin-fixed 0.5-1 ug/mL|Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes|Flow Cytometry 0.5-1 ug/million cells/0.1 mL|Optimal dilution for a specific application should be determined by user
Shipping Conditions: Room temperature
Storage Conditions: 4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: 2 years

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