Anti-Endoglin / CD105 (ENG/1621)

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Dry Ice Shipment: No

Key Features

Custom Services: We offer custom development, testing, and other tailored services for Anti-Endoglin / CD105 (ENG/1621) to help researchers meet specific project requirements with precision.
Bulk Orders: Gentaur provides bulk ordering for Anti-Endoglin / CD105 (ENG/1621), ensuring competitive pricing and fast processing to support institutional and commercial research needs.
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At Gentaur, we recognize the critical role that dependable products play in advancing scientific research. Our selection of reagents, instruments, and solutions, including Anti-Endoglin / CD105 (ENG/1621), is carefully curated to meet the specific needs of today's laboratories. We are committed to providing high-quality tools that support and enhance the progress of innovative research.

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Each product we offer is thoroughly tested to ensure it meets strict industry standards. This commitment guarantees consistent, reproducible results that you can rely on in your research.

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Anti-Endoglin / CD105 (ENG/1621)

CAT:

37-BNUB1621-500

Size:

500 µL

Price:

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For price, please contact [email protected].

Anti-Endoglin / CD105 (ENG/1621)

Description: CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. CD105 is highly expressed in endothelial cells during tumor angiogenesis and inflammation, with weak or negative expression in vascular endothelium of normal tissues. Angiogenesis is a promising prognostic marker in a variety of tumors. Endoglin is a more specific and sensitive marker for tumor angiogenesis than CD31 or CD34, as it labels only newly-formed blood vessels and may serve as a prognostic marker for prostate adenocarcinoma, and cancers of the lung, stomach, breast, and brain._x000D_ _x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_
Synonyms: CD105; END; Endoglin; Eng; HHT1; S-endoglin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ENG
Gene ID: 2022
NCBI Gene ID: 76753
UniProt: P17813
Cellular Locus: Plasma membrane
Host: Mouse
Species Reactivity: Horse, Human, Monkey, Pig, Rat
Immunogen: Recombinant extracellular fragment of human Endoglin protein (exact sequence is proprietary)
Target Antigen: CD105 | Endoglin
Clonality: Monoclonal
Isotype: IgG1 κ
Clone: ENG/1621
Conjugation: Purified, with BSA
Disease: Tumor
Source: Animal
Applications: Flow (verified) | IF (verified)
Validated Applications: FC, IF
Field of Research: Cancer
Positive Control: HeLa, A431 and HL-60 cells. Colon.
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 84 kDa
Additionnal Information: Flow cytometry: 1-2 ug/million cells|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunofluorescence: 2-4 ug/mL|ELISA: For coating order antibody without BSA|For functional studies, order Ab without azide|Optimal dilution for a specific application should be determined by user
Shipping Conditions: Room temperature
Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: 2 years

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