Anti-MMP3 (Marker of Metastasis and Rheumatoid Arthritis)(MMP3/1730)

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Custom Services: We offer custom development, testing, and other tailored services for Anti-MMP3 (Marker of Metastasis and Rheumatoid Arthritis)(MMP3/1730) to help researchers meet specific project requirements with precision.
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At Gentaur, we recognize the critical role that dependable products play in advancing scientific research. Our selection of reagents, instruments, and solutions, including Anti-MMP3 (Marker of Metastasis and Rheumatoid Arthritis)(MMP3/1730), is carefully curated to meet the specific needs of today's laboratories. We are committed to providing high-quality tools that support and enhance the progress of innovative research.

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Anti-MMP3 (Marker of Metastasis and Rheumatoid Arthritis)(MMP3/1730)

CAT:

37-BNUB1730-100

Size:

100 µL

Price:

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Anti-MMP3 (Marker of Metastasis and Rheumatoid Arthritis)(MMP3/1730)

Description: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Synonyms: CHDS6; Matrix metalloproteinase 3; Matrix metalloproteinase-3; MMP3; Proteoglycanase; SL1; STMY1; STR1; Stromelysin-1; Transin 1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MMP3
Gene ID: 4314
NCBI Gene ID: 375129
UniProt: P08254
Cellular Locus: Secreted (extracellular)
Host: Mouse
Species Reactivity: Human
Immunogen: Recombinant full-length human MMP3 protein
Target Antigen: MMP3
Clonality: Monoclonal
Isotype: IgG1 κ
Clone: MMP3/1730
Conjugation: Purified, with BSA
Source: Animal
Positive Control: A431 cells. Prostate or Lung Carcinoma.
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 57 kDa
Additionnal Information: For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry
Shipping Conditions: Room temperature
Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: 2 years

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