Anti-Chromogranin A / CHGA (Neuroendocrine Marker)

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Custom Services: We offer custom development, testing, and other tailored services for Anti-Chromogranin A / CHGA (Neuroendocrine Marker) to help researchers meet specific project requirements with precision.
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At Gentaur, we recognize the critical role that dependable products play in advancing scientific research. Our selection of reagents, instruments, and solutions, including Anti-Chromogranin A / CHGA (Neuroendocrine Marker), is carefully curated to meet the specific needs of today's laboratories. We are committed to providing high-quality tools that support and enhance the progress of innovative research.

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Anti-Chromogranin A / CHGA (Neuroendocrine Marker)

CAT:

37-BNUB1732-100

Size:

100 µL

Price:

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Anti-Chromogranin A / CHGA (Neuroendocrine Marker)

Description: Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Synonyms: Beta-Granin; CGA; CHGA; Chromogranin A Parathyroid Secretory Protein 1; ER-37; Pancreastatin; Parastatin; Parathyroid Secretory Protein 1; Pituitary Secretory Protein I; SP-I; Vasostatin I or II
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CHGA
Gene ID: 1113
NCBI Gene ID: 150793
UniProt: P10645
Cellular Locus: Vesicular
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant human full-length Chromogranin A protein
Target Antigen: CHGA | Chromogranin A
Clonality: Polyclonal
Isotype: IgG κ
Conjugation: Purified, with BSA
Disease: Tumor
Source: Animal
Applications: IHC, FFPE (verified)
Validated Applications: IHC, FFPE
Field of Research: Cancer, Endocrinology
Positive Control: PC12 cells. Adrenal gland, bowel, parathyroid, pancreas, or pheochromocytoma.
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 68-75 kDa
Additionnal Information: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunofluorescence: 1-2 ug/mL|Immunohistology (formalin): 0.25-0.5 ug/mL|Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min|Flow Cytometry 0.5-1 ug/million cells/0.1 mL|Optimal dilution for a specific application should be determined by user
Shipping Conditions: Room temperature
Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: 2 years

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