2'-RIBOTAC-U recruiter-linker

• UNSPSC Description:

  2'-RIBOTAC-U recruiter-linker (Compound 9) consists of RNase L recruiter and linker. 2'-RIBOTAC-U recruiter-linker is reacted separately with 2’-azido-uridine or 5’-azidomethyl-uridine via copper-catalyzed click chemistry, resulting in the formation of 2’-RIBOTAC-U and 5’-RIBOTAC-U, respectively. 2’-RIBOTAC-U has anti-SARS-CoV-2 activity[1].

• Target Antigen:

  Biochemical Assay Reagents

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/2-ribotac-u-recruiter-linker.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC1=CC(/C=C2SC(NC3=CC=CC=C3)=C(C(OCC)=O)C\2=O)=CC=C1OCCOCCOCCOCCNC(CCC#C)=O

• Molecular Weight:

  638.73

• References & Citations:

  [1]Min Y, et al. Developing nucleoside tailoring strategies against SARS-CoV-2 via ribonuclease targeting chimera. Sci Adv. 2024 Apr 12;10(15):eadl4393.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported