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LQ-38

CAT: 0804-HY-168211Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168211Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LQ-38 is an orally active inhibitor for soluble epoxide hydrolase (sEH) with an IC50 of 5.2 nM. LQ-38 exhibits anti-inflammatory activity in rat foot edema model and mouse acute pancreatitis model, exhibits analgesic effect in Acetic acid -induced writhing mouse model[1].
UNSPSC
12352211
Target
Epoxide Hydrolase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lq-38.html
Smiles
C[C@]1(CNC(NCC2CCOCC2)=O)CC[C@]([C@]3([H])C1)(C)CCC(C3=C4)[C@]5(C)CC[C@@]6([H])C(C)(C)[C@@H](O[C@@H]7[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O7)CC[C@]6(C)[C@@]5([H])C4=O
Molecular Formula
C42H68N2O9
Molecular Weight
745.00
References & Citations
[1]Liu Q, et al., Discovery of glycosidated glycyrrhetinic acid derivatives: Natural product-based soluble epoxide hydrolase inhibitors. Eur J Med Chem. 2024 Oct 9;280:116937.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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