LD-38

CAT: 0804-HY-177495Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-177495Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
LD-38 is a drug-linker conjugate for ADC. LD-38 consists of a topoisomerase 1 inhibitor (Exatecan) (HY-13631) and a highly hydrophilic stable and cleavable linker. LD-38 can be used for synthesis of ADC[1][2].
CAS Number
[3094583-35-1]
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC; Topoisomerase
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C(C=CC1=O)N1CCC(NCCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](C(NC2=CC=C(COC(N[C@H]3CCC(C(C)=C(F)C=C4N=C5C6=CC7=C8COC([C@](CC)7O)=O)=C4C3=C5CN6C8=O)=O)C=C2)=O)CCC(NCC[N+](C)(CCCS([O-])(=O)=O)C)=O)=O)=O)=O
Molecular Formula
C67H87FN10O20S
Molecular Weight
1403.53
References & Citations
[1]Wu G, et al. KA-3123-LD38: a novel bispecific antibody-drug conjugate (ADC) targeting EGFR and B7H3 with a DNA topoisomerase I inhibitor payload[J]. Cancer Research, 2025, 85 (8_Supplement_1) : 2132-2132.|[2]Catherine C, et al. An anti_itga2 antibody drug conjugate. WO2025153055A1. 2025-07-24.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Topo I

Related Products

CatalogName
HY-157209LD-ATTEC4
HY-149596PTZ-LD
HY-D3007LD-CK
HY-178825LD-110
HY-157208LD-ATTEC2
HY-151468AIE-Cbz-LD-C7
HY-162862JAK-IN-38
HY-157664HSD17B13-IN-38
HY-169307BTK-IN-38
HY-105491UC-38

Alternative Products

CatalogName
TRC-L372625-100MGLD 4202
598518LD 490
MBS5782185LD-473
MBS5823001PTZ-LD
TBP0078-01Lipoamide Dehydrogenase (LD)
IN12079-01Solvent Blue 38 38
sc-52430IPO-38 (IPO-38)
LD-LSB C-A10LD-LSBC-A10/Stainless Steel Water Bath LD-LSBC- A10
MBS1472201-01Recombinant Drosophila melanogaster Peptidoglycan-recognition protein LD (PGRP-LD), partial
31032Kylt® RA LD 100

Popular Products