EF-1502

CAT: 0804-HY-118931Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-118931Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
EF-1502 is a potent and selective GABA transporter inhibitor with GAT1 and BGT1 inhibitory activity. EF-1502 produces a synergistic anti-epileptic effect when used in combination with Tiagabine (HY-B0696), a compound used to suppress epileptic seizures. The dosing combination of EF-1502 exhibited reduced anti-epileptic efficacy and dyskinesia when used with THIP (HY-10232) . The mechanism of EF-1502 differs significantly from Tiagabine, suggesting a unique role in the inhibitory strategy[1].
CAS Number
[684645-54-3]
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ef-1502.html
Smiles
OC1=NOC2=C1C(CCC2)N(C)CC/C=C(C3=C(C=CS3)C)\C4=C(C=CS4)C
Molecular Formula
C22H26N2O2S2
Molecular Weight
414.58
References & Citations
[1]Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the extrasynaptic GABA (A) receptor agonist gaboxadol
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-U00118-01EF-5
HY-161690EF-4-177
HY-U00118R-01EF-5 (Standard)
HY-P85844EF-1β Antibody (YA5536, Mouse)
HY-P705372-01HLA-B*1502 B2M Monomer, Human (Biotinylated, HEK293, His-Avi)
HY-156829-01PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 1:1)
HY-156829APLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1)
HY-111361-01FN-1501
HY-P991365DS-1501
HY-160698-01SGR-1505

Alternative Products

CatalogName
BET-1502Laboratory High Speed Centrifuge (BET-1502)
BTST-1502Stability Test Chamber BTST-1502
BFU- 1502Single Beam UV Visible Spectrophotometer (BFU- 1502)
803922PIC 1502-TRI 200-B7527 AC Signs
803923PIC 1502-TRI 200-B7525 AC Signs
803924PIC 1502-TRI 315-B7527 AC Signs
803925PIC 1502-TRI 315-B7525 AC Signs
S0B1037-01PSME4 Recombinant Rabbit mAb (S-1502-70)
470192TSFM (COXPD3, EF-TS, EF-Tsmt)
MBS3615292-01EF-5

Popular Products