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GDP-α-D-mannose (disodium)

CAT: 0804-HY-N7389B-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N7389B-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GDP-α-D-mannose disodium is the donor substrate for mannosyltransferases and the precursor of GDP-β-L-fucose. GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (Ki 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (Ki 115 μM) [1].
CAS Number
148296-46-2
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/gdp-α-d-mannose-disodium.html
Purity
99.76
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=P(OP(O[C@@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)(O[Na])=O)(O[Na])OC[C@@H](O2)[C@@H](O)[C@@H](O)[C@@H]2N3C(N=C(N)NC4=O)=C4N=C3
Molecular Formula
C16H23N5Na2O16P2
Molecular Weight
649.30
Precautions
H315, H319, H335
References & Citations
[1]Elling L, et al. Expression, purification and characterization of recombinant phosphomannomutase and GDP-alpha-D-mannose pyrophosphorylase from Salmonella enterica, group B, for the synthesis of GDP-alpha-D-mannose from D-mannose. Glycobiology. 1996 Sep;6 (6) :591-7.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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