GDP-D-Rha6F2

• UNSPSC Description:

  GDP-D-Rha6F2 is an inhibitor of GMDS (GDP-mannose-4,6-dehydratase) and binds to the active site of GMDS. GDP-D-Rha6F2 abolishes the conversion of GDP-mannose[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/gdp-d-rha6f2.html

• Smiles:

  O=C1NC(N)=NC2=C1N=CN2[C@@H]3O[C@H](COP(OP(O[C@@H]4[C@@H](O)[C@@H](O)[C@H](O)[C@@H](C(F)F)O4)([O-])=O)([O-])=O)[C@@H](O)[C@H]3O.[NH4+].[NH4+]

• Molecular Weight:

  659.38

• References & Citations:

  [1]Pijnenborg JFA, et al. Fluorinated rhamnosides inhibit cellular fucosylation. Nat Commun. 2021 Dec 2;12(1):7024.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported