Products for Research Use Only
RegisterLogin

PLN-1474

CAT: 0804-HY-47888-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-47888-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PLN-1474 (compound 1) is an orally active and selective ανβ1 integrin inhibitor with an IC50 value of <50 nM. PLN-1474 reduces levels of pSMAD3/SMAD3 in liver, hepatic collagen gene expression and hepatic OHP concentration in liver fibrosis mouse model. PLN-1474 can be used for the research of preventing, delaying or researching a fibrotic or cirrhotic disease or disorder.
CAS Number
2408065-32-5
UNSPSC
12352005
Target
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pln-1474.html
Purity
99.35
Solubility
DMSO : 70 mg/mL (ultrasonic)
Smiles
O=C(O)[C@H](CCCCCCCC1=CC=C2C(N1)=NCCC2)NC(C3(C)CCOCC3)=O
Molecular Formula
C24H37N3O4
Molecular Weight
431.57
References & Citations
[1]Anderson Kraig, et al. Combination treatment of liver diseases using integrin inhibitors. WO2021127483. 2021.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-13752STA-1474
HY-RS10727PLN Human Pre-designed siRNA Set A
HY-RS17361Pln Mouse Pre-designed siRNA Set A
HY-RS23815Pln Rat Pre-designed siRNA Set A
HY-P72275-01Cardiac phospholamban/PLN, Human (P.pastoris, GST)
HY-122883-01BC-1471
HY-110145MRS 1477
HY-169018CIB-1476
HY-50874BCX 1470
HY-13524-01AG-1478

Alternative Products

CatalogName
BA4588-1PLN-1474
T71426-01STA-1474
A44502-100ULGRIN2B (Ab-1474) Antibody
MBS8503817-01NMDAR2B (Ab-1474) Antibody
GTR18085830Anti-NMDAR2B (Ab-1474)
572610-01PLN
GTR18288095NMDAR2B (Ab-1474) Conjugated Antibody
MBS7006249-01PLN Antibody
G008aPLN gRNA1

Popular Products