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LTA4H-IN-4

CAT: 0804-HY-161349Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161349Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LTA4H-IN-4 (compound 3) is an orally active LTA4H inhibitor. The IC50 value of LTA4H-IN-4 for hERG is 156 μM. LTA4H-IN-4 can be used in inflammation related studies[1].
UNSPSC
12352005
Target
Aminopeptidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lta4h-in-4.html
Solubility
10 mM in DMSO
Smiles
OC1CCN(CC1)CC2=NC=C(OC3=CC=C(C4=CC=NN4)C=N3)C=C2
Molecular Formula
C19H21N5O2
Molecular Weight
351.40
References & Citations
[1]Thoma G, et al. Structure-Guided Elaboration of a Fragment-Like Hit into an Orally Efficacious Leukotriene A4 Hydrolase Inhibitor. J Med Chem. 2024 Mar 28;67 (6) :5093-5108.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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