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LTA4H-IN-2

CAT: 0804-HY-162015Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162015Size:1 Each
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Description
LTA4H-IN-2 (compound (S) -2) is an orally active inhibitor of Leukotriene A4 Hydrolase, with an IC50 of [1].
CAS Number
2851480-52-7
UNSPSC
12352005
Target
Aminopeptidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lta4h-in-2.html
Solubility
10 mM in DMSO
Smiles
N[C@@H](CN1C=CC(C2=CC=C(OC3=NC=C(C4=CC=NN4)C=C3F)C=C2)=N1)CO
Molecular Formula
C20H19FN6O2
Molecular Weight
394.40
References & Citations
[1]Gebhard Thoma, et al. Discovery of Amino Alcohols as Highly Potent, Selective, and Orally Efficacious Inhibitors of Leukotriene A4 Hydrolase. J Med Chem. 2023 Dec 14;66 (23) :16410-16425.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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