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Ketoprofen-13C, d3

CAT: 0804-HY-B0227S2Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0227S2Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ketoprofen-13C, d3 is the 13C- and deuterium labeled Ketoprofen. Ketoprofen (RP-19583) is a non-steroidal antiinflammatory agent, acting as a potent inhibitor of COX, with IC50s of 2 nM and 26 nM for COX-1 and COX-2 in human blood monocytes, respectively[1].
CAS Number
1189508-77-7
Product Name Alternative
RP-19583-13C, d3
UNSPSC
12352005
Target
Apoptosis; COX; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Immunology/Inflammation; Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CC=C1)C2=CC(C([13C]([2H])([2H])[2H])C(O)=O)=CC=C2
Molecular Formula
C15 13CH11D3O3
Molecular Weight
258.29
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.|[2]Palomer A, et al. Structure-based design of cyclooxygenase-2 selectivity into ketoprofen. Bioorg Med Chem Lett. 2002 Feb 25;12 (4) :533-7.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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Alternative Products

CatalogName
AR-K01048-01Ketoprofen-13C-d3
MBS6057879-01rac Ketoprofen-13C,d3
sc-489224(R) - (-) -Ketoprofen-13C, d3
015343Rac Ketoprofen-13C, d3
TRC-K200808-0.5MG(R)-(-)-Ketoprofen-13C,d3
sc-489223(S) - (+) -Ketoprofen-13C, d3
TRC-K200807-2.5MG(S)-(+)-Ketoprofen-13C,d3
sc-489225Rac Ketoprofen amide-13C, d3
sc-218224Dihydro Ketoprofen-13C, d3 (Mixture of Diastereomers)
TRC-D449177-25MGDihydro Ketoprofen-13C,d3(Mixture of Diastereomers)

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