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SCH 206272

CAT: 0804-HY-116958Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116958Size:1 Each
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Description
SCH 206272 is a selective antagonist of the tachykinin (NK) receptor. SCH 206272 inhibits binding at human tachykinin NK (1), NK (2), and NK (3) receptors (Ki = 1.3, 0.4, and 0.3 nM, respectively) . SCH 206272 has an orally active[1].
CAS Number
226915-43-1
UNSPSC
12352005
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sch-206272.html
Smiles
O=C(C1=CC(Cl)=CC(Cl)=C1)N(C)C/C([C@@H](C2=CC(Cl)=C(C=C2)Cl)CCN3CCC(N4C([C@H](CCC4)CC(NC)=O)=O)CC3)=N\OC
Molecular Formula
C33H41Cl4N5O4
Molecular Weight
713.52
References & Citations
[1]John C Anthes, et al. SCH 206272: a potent, orally active tachykinin NK (1), NK (2), and NK (3) receptor antagonist. Eur J Pharmacol. 2002 Aug 23;450 (2) :191-202.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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