JAK-IN-21
CAT:
804-HY-148060-04
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
JAK-IN-21
- CAS Number: 2445499-20-5
- UNSPSC Description: JAK-IN-21 (Example 4) is a selective and potent JAK inhibitor with IC50s of 1.73, 2.04, 109 and 62.9 nM against JAK1, JAK2, J2V617F and TYK2, respectively[1].
- Target Antigen: JAK
- Type: Reference compound
- Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/jak-in-21.html
- Solubility: DMSO : 125 mg/mL (ultrasonic)
- Smiles: N#CCNC(C1=CC=C(C2=NC(NC3=CN(CC#N)N=C3)=NC=C2C)C=C1)=O
- Molecular Weight: 372.38
- References & Citations: [1]Zhaokui WAN, et al. Benzamides of pyrazolyl-amino-pyrimidinyl derivatives, and compositions and methods thereof. Patent WO2020119819.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported