Products for Research Use Only
RegisterLogin

JAK-IN-36

CAT: 0804-HY-161259Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-161259Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
JAK-IN-36 (Compound 12e) is a potent and selective inhibitor of Janus Kinase 1 (JAK1) with a IC50 value of 2.2 nM. JAK-IN-36 can be used in the study of autoimmune diseases[1].
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/jak-in-36.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC(CN2CCC(NC3=C4C(NC=C4)=NC=C3C5=CNN=C5)CC2)=CC=C1
Molecular Formula
C22H23ClN6
Molecular Weight
406.91
References & Citations
[1]Chen L, et al. Design, synthesis and evaluation of C-5 substituted pyrrolopyridine derivatives as potent Janus Kinase 1 inhibitors with excellent selectivity. Eur J Med Chem. 2024 Mar 5;267:116210.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
JAK1

Related Products

CatalogName
HY-111471JAK-IN-5
HY-18301-01JAK-IN-35
HY-151262-01JAK-IN-23
HY-157011JAK-IN-33
HY-143444-01JAK-IN-20
HY-111749JAK-IN-4
HY-144057JAK-IN-17
HY-14986JAK-IN-32
HY-46262JAK-IN-15
HY-139807-01JAK-IN-14

Alternative Products

CatalogName
T209065-01JAK-IN-36
BA4919-10JAK-IN-14
BA4937-1JAK-IN-30
BA4922-1JAK-IN-24
JDC67353-01JAK-IN-1
T210131-01JAK-IN-37
T12549-01JAK-IN-11
T79222-01JAK-IN-29
T73250-01JAK-IN-17
MBS3844679-01JAK-IN-4

Popular Products