Desmethyl Levofloxacin-d8 (hydrochloride)

• UNSPSC Description:

  Desmethyl Levofloxacin-d8 hydrochloride is the deuterium labeled Desmethyl Levofloxacin. Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication[1].

• Target Antigen:

  Antibiotic; Drug Metabolite; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Anti-infection;Metabolic Enzyme/Protease;Others

• Field of Research:

  Infection

• Smiles:

  O=C1C2=CC(F)=C(N3C([2H])([2H])C([2H])([2H])NC([2H])([2H])C3([2H])[2H])C4=C2N(C=C1C(O)=O)[C@@H](C)CO4.Cl

• Molecular Weight:

  391.85

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Siva, R., et al., Effect of levofloxacin on neutrophilic airway inflammation in stable COPD: a randomized, double-blind, placebo-controlled trial. Int J Chron Obstruct Pulmon Dis, 2014. 9: p. 179-86.

• Shipping Conditions:

  Room temperature

• CAS Number:

  1217677-38-7