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Levofloxacin-d8

CAT: 0804-HY-B0330S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0330S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Levofloxacin-d8 is the deuterium labeled Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
CAS Number
1217716-71-6
Product Name Alternative
(-) -Ofloxacin-d8
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection
Field of Research
Infection
Purity
99.84
Solubility
10 mM in DMSO|DMSO : 10mg/mL (ultrasonic) |H2O : ≥ 5mg/mL
Smiles
O=C1C2=CC(F)=C(N3C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C3([2H])[2H])C)C4=C2N(C=C1C(O)=O)[C@@H](C)CO4
Molecular Formula
C18H12D8FN3O4
Molecular Weight
369.42
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Siva, R., et al., Effect of levofloxacin on neutrophilic airway inflammation in stable COPD: a randomized, double-blind, placebo-controlled trial. Int J Chron Obstruct Pulmon Dis, 2014. 9: p. 179-86.; Pradeep, A.R., et al., Clinical and microbiological effects of levofloxacin in the treatment of chronic periodontitis: a randomized, placebo-controlled clinical trial. J Investig Clin Dent, 2014.; Lee, B.T., et al., Efficacy of Levofloxacin in the Treatment of BK Viremia: A Multicenter, Double-Blinded, Randomized, Placebo-Controlled Trial. Clin J Am Soc Nephrol, 2014.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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Alternative Products

CatalogName
TMID-0195-01Levofloxacin-d8
AR-L01507-01Levofloxacin-d8 HCl
453693-01Levofloxacin-d8 Chloromethyl Ester
AR-L01501-01N-Desmethyl Levofloxacin-d8
sc-218152Desmethyl Levofloxacin-d8 Hydrochloride
AR-L07058-01Levofloxacin EP Impurity B-d8 Trifluoroacetate (Levofloxacin USP Related Compound A-d8 Trifluoroacetate, N-Desmethyl Levofloxacin-d8 Trifluoroacetate)
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