Virodhamine (TFA)

CAT: 0804-HY-110194Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-110194Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Virodhamine TFA is an endocannabinoid, it regulates neurotransmission by activating the cannabinoid (CB) receptors. Virodhamine is an antagonist of CB1 receptor and an agonist of CB2 receptor. Virodhamine TFA induces megakaryocytic differentiation by triggering MAPK signaling and ROS production. Virodhamine TFA can be used for the research of various neurological disorders such as Alzheimer's and Parkinson's diseases[1][2].
CAS Number
[1415264-56-0]
UNSPSC
12352211
Target
Cannabinoid Receptor; Endogenous Metabolite
Type
Reference compound
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/virodhamine-tfa.html
Smiles
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(OCCN)=O.OC(C(F)(F)F)=O
Molecular Formula
C24H38F3NO4
Molecular Weight
461.56
References & Citations
[1]Sharma DS, et al. Virodhamine, an endocannabinoid, induces megakaryocyte differentiation by regulating MAPK activity and function of mitochondria. J Cell Physiol. 2021 Feb;236 (2) :1445-1453.|[2]Hayase T. Working memory- and anxiety-related behavioral effects of repeated nicotine as a stressor: the role of cannabinoid receptors. BMC Neurosci. 2013 Feb 9;14:20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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