SCFSkp2-IN-2
CAT:
804-HY-148900-06
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
SCFSkp2-IN-2
- CAS Number: 1375060-02-8
- UNSPSC Description: SCFSkp2-IN-2 (Compound AAA-237) is a Skp2 inhibitor with a KD of 28.77 μM. AAA-237 induces apoptosis of NSCLC cells and shows antitumor activities[1].
- Target Antigen: E1/E2/E3 Enzyme
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/scfskp2-in-2.html
- Solubility: DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: CCN(C1=CC(O)=C(C=C1)/C=N/NC(C2=CN=CC=C2)=O)CC
- Molecular Weight: 312.37
- References & Citations: [1]Liu J, et al. Anti-tumor effects of Skp2 inhibitor AAA-237 on NSCLC by arresting cell cycle at G0/G1 phase and inducing senescence. Pharmacol Res. 2022 Jul;181:106259.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported