Dexamethasone (GMP)

Dexamethasone (GMP)

• CAS Number: 50-02-2
• UNSPSC Description: Dexamethasone (Hexadecadrol) (GMP) is Dexamethasone (HY-14648) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Dexamethasone is an agonist of glucocorticoid receptor[1][2][3][4].
• Target Antigen: ADC Cytotoxin; Glucocorticoid Receptor
• Type: GMP Small Molecules
• Related Pathways: Antibody-drug Conjugate/ADC Related;Immunology/Inflammation;Vitamin D Related/Nuclear Receptor
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Cancer; Infection; Endocrinology; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/dexamethasone-gmp.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C=C[C@]2(C(CC[C@@]3([C@@]2([C@H](C[C@]4([C@]3(C[C@H]([C@]4(O)C(CO)=O)C)[H])C)O)F)[H])=C1)C
• Molecular Weight: 392.46
• References & Citations: [1]Grigoriadis AE, et al. Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone-derived clonal cell population: effect of dexamethasone. J Cell Biol. 1988 Jun;106(6):2139-51.|[2]Tenenbaum HC, Heersche JN. Dexamethasone stimulates osteogenesis in chick periosteum in vitro. Endocrinology. 1985 Nov;117(5):2211-7.|[3]Rickard DJ, et al. Induction of rapid osteoblast differentiation in rat bone marrow stromal cell cultures by dexamethasone and BMP-2. Dev Biol. 1994 Jan;161(1):218-28.|[4]Alliot-Licht B, et al. Dexamethasone stimulates differentiation of odontoblast-like cells in human dental pulp cultures. Cell Tissue Res. 2005 Sep;321(3):391-400.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported