Dexamethasone

CAT: 0400-SIH-259-5GSize: 5 gDry Ice: NoHazardous: No
CAT#:0400-SIH-259-5GSize:5 g
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Background
Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs. It is an anti-inflammatory and immunosuppressant. In cancer patients, it can be give to augment the antiemetic effect of 5-HT3 receptor antagonists, and is also used to counteract the development of edema (1). In a diagnostic setting, it is used to suppress the natural pituitary-adrenal axis (2).
Description
Glucocorticoid receptor ligand
CAS Number
50-02-2
Product Name Alternative
(11β,16α) -9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
UNSPSC
41116105
Type
Inducer
Source
Synthetic
Field of Research
Cancer | Apoptosis
Purity
>98%
Weight
5
Format
White solid
Solubility
Soluble to 100 mM in DMSO
Molecular Formula
C22H29FO5
Molecular Weight
392.47
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Roila F., and Fatigoni S. (2006) Ann Oncol.17 (Suppl2): ii96-ii100. 2. Hasan E.A., Jessop D.S., Power L.L. Monk P.T. and Kirwan J.R. (2009) Int J Endocrinol. 2009: 391284.

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