Dexamethasone

• Target :

  Glucocorticoid Receptor|||ADC Cytotoxin|||Autophagy|||Mitophagy|||SARS-CoV|||IL Receptor|||Complement System|||Antibiotic|||Antibacterial

• Related Pathways :

  Antibody-drug Conjugate/ADC Related|||Immunology/Inflammation|||Endocrinology/Hormones|||Autophagy|||Microbiology/Virology

• Purity :

  0.9991

• Bioactivity :

  Dexamethasone is a glucocorticoid receptor agonist and IL receptor modulator with anti-inflammatory, immunosuppressive, and apoptosis-inducing activities. It inhibits the production of inflammatory miRNA-155 exosomes in macrophages, significantly reduces inflammatory cytokine expression in neutrophils and monocytes, suppresses LPS-induced macrophage inflammation, and induces autophagy. It is commonly used to induce animal models of depression, muscle atrophy, and hypertension, and holds potential in COVID-19 research.

• Smiles :

  F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(CO)=O)(O)[C@H](C)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]

• Molecular Formula :

  C22H29FO5

• Molecular Weight :

  392.46

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  50-02-2