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Dexamethasone

CAT: 0931-T1076-01Size: 50 mgDry Ice: NoHazardous: No
CAT#:0931-T1076-01Size:50 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
50-02-2
Target
Glucocorticoid Receptor|||ADC Cytotoxin|||Autophagy|||Mitophagy|||SARS-CoV|||IL Receptor|||Complement System|||Antibiotic|||Antibacterial
Related Pathways
Antibody-drug Conjugate/ADC Related|||Immunology/Inflammation|||Endocrinology/Hormones|||Autophagy|||Microbiology/Virology
Purity
0.9991
Bioactivity
Dexamethasone is a glucocorticoid receptor agonist and IL receptor modulator with anti-inflammatory, immunosuppressive, and apoptosis-inducing activities. It inhibits the production of inflammatory miRNA-155 exosomes in macrophages, significantly reduces inflammatory cytokine expression in neutrophils and monocytes, suppresses LPS-induced macrophage inflammation, and induces autophagy. It is commonly used to induce animal models of depression, muscle atrophy, and hypertension, and holds potential in COVID-19 research.
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F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(CO)=O)(O)[C@H](C)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]
Molecular Formula
C22H29FO5
Molecular Weight
392.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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