SLIGRL-NH2 (TFA)

SLIGRL-NH2 (TFA)

• CAS Number: 2828432-39-7
• UNSPSC Description: SLIGRL-NH2 TFA (Protease-Activated Receptor-2 Activating Peptide TFA) is an agonist of Protease-Activated Receptor-2 (PAR-2)[1].
• Target Antigen: Protease Activated Receptor (PAR)
• Type: Peptides
• Related Pathways: GPCR/G Protein
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/sligrl-nh2-tfa.html
• Solubility: H2O
• Smiles: OC[C@H](N)C(N[C@@H](CC(C)C)C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC(C)C)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
• Molecular Weight: 770.84
• References & Citations: [1]Akiyama T, et al. Behavioral model of itch, alloknesis, pain and allodynia in the lower hindlimb and correlativeresponses of lumbar dorsal horn neurons in the mouse. Neuroscience. 2014 Apr 25;266:38-46.|[2]Li Y, et al. Perivascular adipose tissue-derived relaxing factors: release by peptide agonists via proteinase-activated receptor-2 (PAR2) and non-PAR2 mechanisms. Br J Pharmacol. 2011 Dec;164(8):1990-2002.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported