VKGILS-NH2 (TFA)

VKGILS-NH2 (TFA)

• CAS Number: 2828432-41-1
• UNSPSC Description: VKGILS-NH2 TFA is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist). VKGILS-NH2 TFA has no effect on DNA synthesis in cells[1][2].
• Target Antigen: Protease Activated Receptor (PAR)
• Type: Peptides
• Related Pathways: GPCR/G Protein
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/vkgils-nh2-tfa.html
• Solubility: 10 mM in DMSO
• Smiles: OC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)NC(CNC([C@H](CCCCN)NC([C@H](C(C)C)N)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F
• Molecular Weight: 728.80
• References & Citations: [1]M Tognetto, et al. Evidence That PAR-1 and PAR-2 Mediate Prostanoid-Dependent Contraction in Isolated Guinea-Pig Gallbladder. Br J Pharmacol. 2000 Oct;131(4):689-94.|[2]David A Vesey, et al. Proinflammatory and Proliferative Responses of Human Proximal Tubule Cells to PAR-2 Activation. Am J Physiol Renal Physiol. 2007 Nov;293(5):F1441-9.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported