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FFN511 (hydrochloride)

CAT: 0804-HY-103465BSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-103465BSize:1 Each
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Description
FFN511 (hydrochloride) is a potent fluorescent false neurotransmitters (FFNs) that targets neuronal vesicular monoamine transporter 2 (VMA T2) . FFN511 (hydrochloride) inhibits serotonin binding to VMA T2-containing membranes with an IC50 of 1 µM. FFN511 (hydrochloride) directly images the dynamics of release during exocytosis, can be used to label dopamine terminals in live cortical-striatalacute slices[1][2].
CAS Number
2596358-28-8
UNSPSC
12352005
Target
Monoamine Transporter
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ffn511-hydrochloride.html
Smiles
O=C1OC2=C(C(CCN)=C1)C=C3C4=C2CCCN4CCC3.Cl
Molecular Formula
C17H21ClN2O2
Molecular Weight
320.81
References & Citations
[1]Gubernator NG, et al. Fluorescent false neurotransmitters visualize dopamine release from individual presynaptic terminals. Science. 2009 Jun 12;324 (5933) :1441-4.|[2]Keighron JD, et al. Analytical tools to monitor exocytosis: a focus on new fluorescent probes and methods. Analyst. 2012 Apr 21;137 (8) :1755-63.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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