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FFN511

CAT: 0804-HY-103465-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-103465-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FFN511 is a potent fluorescent false neurotransmitters (FFNs) that targets neuronal vesicular monoamine transporter 2 (VMA T2) . FFN511 inhibits serotonin binding to VMA T2-containing membranes with an IC50 of 1 μM. FFN511 directly images the dynamics of release during exocytosis, can be used to label dopamine terminals in live cortical-striatalacute slices[1][2].
CAS Number
1004548-96-2
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Monoamine Transporter
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ffn511.html
Purity
99.40
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C=C(CCN)C2=CC3=C4N(CCC3)CCCC4=C2O1
Molecular Formula
C17H20N2O2
Molecular Weight
284.35
Precautions
H315, H319, H335
References & Citations
[1]Gubernator NG, et al. Fluorescent false neurotransmitters visualize dopamine release from individual presynaptic terminals. Science. 2009 Jun 12;324 (5933) :1441-4.|[2]Keighron JD, et al. Analytical tools to monitor exocytosis: a focus on new fluorescent probes and methods. Analyst. 2012 Apr 21;137 (8) :1755-63.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
sc-391012AFFN511 trifluoroacetate salt
217358FFN511 (Fluorescent False Neurotransmitter 511, Vesicle Monoamine Transporter (VMAT2) Substrate, FFN511)

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