Cefazolin (sodium)

CAT: 0804-HY-B1078-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B1078-01Size:100 mg
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Description
Cefazolin sodium is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research[1]. Cefazolin sodium has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD) [2].
CAS Number
[27164-46-1]
Product Name Alternative
Cephazolin (sodium)
UNSPSC
12352005
Hazard Statement
H317, H334
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology; Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Cefazolin-sodium.html
Purity
98.45
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL
Smiles
O=C(C(N12)=C(CSC3=NN=C(C)S3)CS[C@]2([H])[C@H](NC(CN4N=NN=C4)=O)C1=O)O[Na]
Molecular Formula
C14H13N8NaO4S3
Molecular Weight
476.49
Precautions
H317, H334
References & Citations
[1]R Quintiliani, et al. Cefazolin. Ann Intern Med. 1978 Nov;89 (5 Pt 1) :650-6.|[2]Peng Liang, et al. Perioperative use of cefazolin ameliorates postoperative cognitive dysfunction but induces gut inflammation in mice. J Neuroinflammation. 2018 Aug 22;15 (1) :235.|[3]Barbara Żyżyńska-Granica, et al. The anti-inflammatory potential of cefazolin as common gamma chain cytokine inhibitor. Sci Rep. 2020 Feb 19;10 (1) :2886.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β-lactam
Citation 01
ACS Omega. 2022 Mar 3;7 (10) :9004-9014.|Emerg Microbes Infect. 2024 Dec;13 (1) :2321981.|Front Aging Neurosci. 2021 Oct 13;13:748637.|iScience. 2022 Jan 5;25 (2) :103731.|ACS Environ Au. 2025 Aug 8.|Anal Chem. 2025 Jun 3;97 (21) :11099-11109.|bioRxiv. 2024 May 10.|Diagn Microbiol Infect Dis. 2025 Nov 4;114 (2) :117181.|mSystems. 2023 Dec 21;8 (6) :e0102623.|Nat Commun. 2022 Mar 2;13 (1) :1116.

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