5-LOX-IN-1

5-LOX-IN-1

• CAS Number: 55040-82-9
• UNSPSC Description: 5-LOX-IN-1 (compound 2b) is an inhibitor of human 5-Lipoxygenase (5-LOX) with an IC50 value of 2.3 μM. 5-LOX-IN-1 can be used for the research of inflammation[1].
• Target Antigen: Lipoxygenase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/5-lox-in-1.html
• Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=C(C1=C(C2=CC=CC=C2)N=C(N3CCOCC3)S1)C4=CC=CC=C4
• Molecular Weight: 350.43
• References & Citations: [1]Sinha S, et al. Design, synthesis and identification of novel substituted 2-amino thiazole analogues as potential anti-inflammatory agents targeting 5-lipoxygenase. Eur J Med Chem. 2018 Oct 5;158:34-50.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported