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Memantine hydrochloride

CAT: 0024-sc-203628Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0024-sc-203628Size:50 mg
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CAS Number
41100-52-1

Chemical Information

Memantine Hydrochloride

Memantine hydrochloride is a hydrochloride obtained by reaction of memantine with one equivalent of hydrochloric acid. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels. It has a role as an antidepressant, an antiparkinson drug, a dopaminergic agent, a NMDA receptor antagonist and a neuroprotective agent. It contains a memantinium(1+).

CAS Number41100-52-1
PubChem CID181458
IUPAC Name3,5-dimethyladamantan-1-amine;hydrochloride
Molecular FormulaC12H22ClN
Molecular Weight215.76
Topological Polar Surface Area26
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Heavy Atom Count14
Formal Charge0
Complexity240
SMILES
CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl
InChI
InChI=1S/C12H21N.ClH/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10;/h9H,3-8,13H2,1-2H3;1H
InChIKey
LDDHMLJTFXJGPI-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Memantine Hydrochloride
CAS: 41100-52-1
CID: 181458
Formula: C12H22ClN
MW: 215.76
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight215.76
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass215.1440774
Monoisotopic Mass215.1440774
Topological Polar Surface Area26 Ų
Heavy Atom Count14
Formal Charge0
Complexity240
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes