AH 11110A

• Description:

  AH 11110A is an α1B-adrenoceptor antagonist, but it can't effectively distinguish between the different subtypes of alpha (1) adrenoceptors (A, B, and D), nor can it clearly differentiate between alpha (1) and alpha (2) adrenoceptors[1][2].

• UNSPSC:

  12352005

• Target:

  Adrenergic Receptor

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Neurological Disease; Cardiovascular Disease

• Smiles:

  OC(CC(N1CCCCC1)=N)COC2=C(C3=CC=CC=C3)C=CC=C2.Cl

• Molecular Formula:

  C21H27ClN2O2

• Molecular Weight:

  374.90

• References & Citations:

  [1]M Eltze, et al. Failure of AH11110A to functionally discriminate between alpha (1) -adrenoceptor subtypes A, B and D or between alpha (1) - and alpha (2) -adrenoceptors. Eur J Pharmacol. 2001 Mar;415 (2-3) :265-76.|[2]Hua Zhang, et al. Different alpha-adrenoceptors mediate migration of vascular smooth muscle cells and adventitial fibroblasts in vitro. Am J Physiol Heart Circ Physiol. 2002 Jun;282 (6) :H2364-70.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  α adrenergic receptor

• CAS Number:

  [179388-65-9]