DC-BPi-03

DC-BPi-03

• CAS Number: 2758411-46-8
• UNSPSC Description: DC-BPi-03 is a potent BPTF-BRD inhibitor with an IC50 of 698.3 nM and a Kd of 2.81 μM[1].
• Target Antigen: Epigenetic Reader Domain
• Type: Reference compound
• Related Pathways: Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/dc-bpi-03.html
• Solubility: DMSO : 33.33 mg/mL (ultrasonic;warming;heat to 80°C)
• Smiles: O=S(C1=NC(C2=CC3=C(NC=C3)C=C2)=CC(NC)=N1)(C)=O
• Molecular Weight: 302.35
• References & Citations: [1]Tian Lu, et al. Discovery of High-Affinity Inhibitors of the BPTF Bromodomain. J Med Chem. 2021 Aug 26;64(16):12075-12088.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported