PTK7/β-catenin-IN-6

PTK7/β-catenin-IN-6

• CAS Number: 1219439-82-3
• UNSPSC Description: PTK7/β-catenin-IN-6 (Compound 03653) is an inhibitor for PTK7/β-catenin interaction, which inhibits the Wnt signaling pathway, and exhibits an anticancer activity against colorectal cancer (CRC)[1].
• Target Antigen: Wnt; β-catenin
• Type: Reference compound
• Related Pathways: Stem Cell/Wnt
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/ptk7-β-catenin-in-6.html
• Solubility: DMSO : 73.33 mg/mL (ultrasonic)
• Smiles: O=C(N1C2=C(NC(C1CC(NC3=CC=C(C(Cl)=C3)Cl)=O)=O)C=CC=C2)/C=C/C4=CC=CC=C4
• Molecular Weight: 480.34
• References & Citations: [1]Ganier L, et al., Discovery of Small-Molecule Inhibitors of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer. ACS Chem Biol. 2022 May 20;17(5):1061-1072.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported