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L-Ascorbic acid (sodium salt) (Standard)

CAT: 0804-HY-B0166AR-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0166AR-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-Ascorbic acid (sodium salt) (Standard) is the analytical standard of L-Ascorbic acid (sodium salt) . This product is intended for research and analytical applications. L-Ascorbic acid sodium salt (Sodium ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid sodium salt selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid sodium salt is also a collagen deposition enhancer and an elastogenesis inhibitor[1][2][3].
CAS Number
134-03-2
Product Name Alternative
Sodium ascorbate (Standard) ; Sodium L-ascorbate (Standard) ; Vitamin C (sodium salt) (Standard)
UNSPSC
12352005
Hazard Statement
H319
Target
Apoptosis; Calcium Channel; Endogenous Metabolite; Reactive Oxygen Species (ROS) ; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/l-ascorbic-acid-sodium-salt-standard.html
Smiles
O[C@@H](CO)[C@]1([H])C(O[Na])=C(O)C(O1)=O
Molecular Formula
C6H7NaO6
Molecular Weight
198.11
Precautions
P264-P280-P305+P351+P338
References & Citations
[1]Hinek A, et al. Sodium L-ascorbate enhances elastic fibers deposition by fibroblasts from normal and pathologic human skin. J Dermatol Sci. 2014 Sep;75 (3) :173-82.|[2]Yang X, et al. Mouse melanoma cell line B16F10-derived conditioned medium inhibits sodium L-ascorbate-induced B16F10 cell apoptosis. Nan Fang Yi Ke Da Xue Xue Bao. 2012 Feb;32 (2) :146-50.|[3]Morimura K, et al. Lack of urinary bladder carcinogenicity of sodium L-ascorbate in human c-Ha-ras proto-oncogene transgenic rats. Toxicol Pathol. 2005;33 (7) :764-7.|[4]Takagi H, et al. Limited tumor-initiating activity of phenylethyl isothiocyanate by promotion with sodium L-ascorbate in a rat two-stage urinary bladder carcinogenesis model. Cancer Lett. 2005 Mar 10;219 (2) :147-53.|[5]Aleksander Hinek, et al. Sodium L-ascorbate enhances elastic fibers deposition by fibroblasts from normal and pathologic human skin. J Dermatol Sci. 2014 Sep;75 (3) :173-82.|[6]Michael T Nelson, et al. Molecular mechanisms of subtype-specific inhibition of neuronal T-type calcium channels by ascorbate. J Neurosci. 2007 Nov 14;27 (46) :12577-83.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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