RB-005

• UNSPSC Description:

  RB-005 is a selective inhibitor of sphingosine kinase 1 (SK1) (IC50=3.6 µM), with weaker inhibition of another isoenzyme, SK2. The selective inhibition of RB-005 helps to distinguish the biological functions and roles of SK1 and SK2, which can be used in the study of inflammatory diseases and cancer[1].

• Target Antigen:

  SphK

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/rb-005.html

• Smiles:

  CCCCCCCCC1=CC=C(CCN2CCC(O)CC2)C=C1

• Molecular Weight:

  317.51

• References & Citations:

  [1]Baek D J, et al. Structure–activity relationships and molecular modeling of sphingosine kinase inhibitors[J]. Journal of medicinal chemistry, 2013, 56(22): 9310-9327.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1425049-20-2