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RL5a

CAT: 0804-HY-138886-02Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-138886-02Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RL5a (compund C23) is a SETD8 inhibitor[1].
CAS Number
133671-66-6
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rl5a.html
Purity
99.6
Solubility
DMSO : 40 mg/mL (ultrasonic; warming)
Smiles
CN(C)CCNC1=CC(C2=CC=CO2)=NC3=CC=CC=C13
Molecular Formula
C17H19N3O
Molecular Weight
281.35
References & Citations
[1]Gardner NJ, et al. The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines. Cell Chem Biol. 2017 Aug 17;24 (8) :981-992.e4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

1,2-Ethanediamine, N'-(2-(2-furanyl)-4-quinolinyl)-N,N-dimethyl-
CAS Number133671-66-6
PubChem CID453072
IUPAC NameN-[2-(furan-2-yl)quinolin-4-yl]-N',N'-dimethylethane-1,2-diamine
Molecular FormulaC17H19N3O
Molecular Weight281.35
XLogP3
Topological Polar Surface Area41.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Heavy Atom Count21
Formal Charge0
Complexity323
SMILES
CN(C)CCNC1=CC(=NC2=CC=CC=C21)C3=CC=CO3
InChI
InChI=1S/C17H19N3O/c1-20(2)10-9-18-15-12-16(17-8-5-11-21-17)19-14-7-4-3-6-13(14)15/h3-8,11-12H,9-10H2,1-2H3,(H,18,19)
InChIKey
CRGKLHXVNVZAPA-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1,2-Ethanediamine, N'-(2-(2-furanyl)-4-quinolinyl)-N,N-dimethyl-
CAS: 133671-66-6
CID: 453072
Formula: C17H19N3O
MW: 281.35
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight281.35
XLogP33
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Exact Mass281.152812238
Monoisotopic Mass281.152812238
Topological Polar Surface Area41.3 Ų
Heavy Atom Count21
Formal Charge0
Complexity323
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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