Lofexidine (hydrochloride)
CAT:
804-HY-B1052-01
Size:
100 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Lofexidine (hydrochloride)
- CAS Number: 21498-08-8
- UNSPSC Description: Lofexidine (hydrochloride) is a selective α2-receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal[1][2].
- Target Antigen: Adrenergic Receptor
- Type: Reference compound
- Related Pathways: GPCR/G Protein;Neuronal Signaling
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Neurological Disease; Endocrinology
- Assay Protocol: https://www.medchemexpress.com/Lofexidine-hydrochloride.html
- Purity: 99.94
- Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : ≥ 100 mg/mL
- Smiles: CC(C1=NCCN1)OC2=C(Cl)C=CC=C2Cl.[H]Cl
- Molecular Weight: 295.59
- References & Citations: [1]Vartak AP, et al. The preclinical discovery of lofexidine for the treatment of opiate addiction. Expert Opin Drug Discov. 2014 Nov;9(11):1371-7.|[2]Gish EC, et al. Lofexidine, an {alpha}2-receptor agonist for opioid detoxification. Ann Pharmacother. 2010 Feb;44(2):343-51.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: Launched