1-[3’-O-[(4,4’-Dimethoxytriphenyl)methyl]-a-L-threofuranosyl]-N4-benzoylcytosine
CAT:
804-HY-W048504
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
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1-[3’-O-[(4,4’-Dimethoxytriphenyl)methyl]-a-L-threofuranosyl]-N4-benzoylcytosine
- CAS Number: 325683-91-8
- UNSPSC Description: 1-[3’-O-[(4,4’-Dimethoxytriphenyl)methyl]-a-L-threofuranosyl]-N4-benzoylcytosine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
- Target Antigen: Nucleoside Antimetabolite/Analog
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/1-3-o-4-4-dimethoxytriphenyl-methyl-a-l-threofuranosyl-n4-benzoylcytosine.html
- Solubility: 10 mM in DMSO
- Smiles: O[C@@H]1[C@@H](OC(C2=CC=C(OC)C=C2)(C3=CC=CC=C3)C4=CC=C(OC)C=C4)CO[C@H]1N5C(N=C(NC(C6=CC=CC=C6)=O)C=C5)=O
- Molecular Weight: 619.66
- References & Citations: [1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported