1-(3’-O-[4,4’-Dimethoxytrityl]-alpha-L-threofuranosyl)uridine

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804-HY-154526

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CAS Number: 325683-90-7
UNSPSC Description: 1-(3’-O-[4,4’-dimethoxytrityl]-alpha-L-threofuranosyl)uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen: Nucleoside Antimetabolite/Analog
Type: Oligonucleotides
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/1-3-o-4-4-dimethoxytrityl-alpha-l-threofuranosyl-uridine.html
Solubility: 10 mM in DMSO
Smiles: O[C@@H]1[C@H](OC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)CO[C@H]1N5C(NC(C=C5)=O)=O
Molecular Weight: 516.54
References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-154526	1-(3’-O-[4,4’-Dimethoxytrityl]-alpha-L-threofuranosyl)uridine
HY-154319	1-(3’-O-[4,4’-Dimethoxytrityl]-alpha-L-threofuranosyl)-thymine
HY-154543	5’-O-(4,4’-Dimethoxytrityl)-3’-O-(2-methoxyethyl) uridine
HY-W048504	1-[3’-O-[(4,4’-Dimethoxytriphenyl)methyl]-a-L-threofuranosyl]-N4-benzoylcytosine
HY-154466-04	5’-O-(4,4’-Dimethoxytrityl)-3’-O-methyluridine
HY-154466-03	5’-O-(4,4’-Dimethoxytrityl)-3’-O-methyluridine
HY-154466-01	5’-O-(4,4’-Dimethoxytrityl)-3’-O-methyluridine
HY-154466-05	5’-O-(4,4’-Dimethoxytrityl)-3’-O-methyluridine
HY-154466-02	5’-O-(4,4’-Dimethoxytrityl)-3’-O-methyluridine
HY-154608	3'-Deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluoro uridine-2'-CED-phosphoramidite

Cat	Name
TNU1627-50mg	1-(3’-O-[4,4’-dimethoxytrityl]-alpha-L-threofuranosyl)uridine
TNU1627-1mg	1-(3’-O-[4,4’-dimethoxytrityl]-alpha-L-threofuranosyl)uridine
TNU1627-1g	1-(3’-O-[4,4’-dimethoxytrityl]-alpha-L-threofuranosyl)uridine
TNU1627-10mg	1-(3’-O-[4,4’-dimethoxytrityl]-alpha-L-threofuranosyl)uridine
TNU1627-5mg	1-(3’-O-[4,4’-dimethoxytrityl]-alpha-L-threofuranosyl)uridine
MBS5827216	1-(3'-O-[4,4'-dimethoxytrityl]-alpha-L-threofuranosyl)uridine
TNU1337-1mg	1-(3’-O-[4,4’-Dimethoxytrityl]-alpha-L-threofuranosyl)-thymine
TNU1337-5mg	1-(3’-O-[4,4’-Dimethoxytrityl]-alpha-L-threofuranosyl)-thymine
TNU1337-1g	1-(3’-O-[4,4’-Dimethoxytrityl]-alpha-L-threofuranosyl)-thymine
TNU1337-50mg	1-(3’-O-[4,4’-Dimethoxytrityl]-alpha-L-threofuranosyl)-thymine