N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-5-methyl-2’-deoxycytidine

N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-5-methyl-2’-deoxycytidine

• UNSPSC Description: N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-5-methyl-2’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/n4-acetyl-5-o-4-4-dimethoxytrityl-5-methyl-2-deoxycytidine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1C[C@H](N2C(N=C(NC(C)=O)C(C)=C2)=O)O[C@@H]1COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5
• Molecular Weight: 585.65
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported