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KRCA-0713

CAT: 0804-HY-120663Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120663Size:1 Each
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Description
KRCA-0713 is an ALK inhibitor with anti-ALK activity. KRCA-0713 showed promising anti-ALK activity in enzyme and cell-based experiments. KRCA-0713 was shown to effectively inhibit ALK-driven tumor growth in H3122 xenograft model studies, similar to the effect of ceritinib[1].
CAS Number
1884321-89-4
UNSPSC
12352005
Target
Anaplastic lymphoma kinase (ALK)
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/krca-0713.html
Smiles
O=S(C1=C(NC2=NC(NC3=C(OC)C=C(C(C)(C(CC4)N)C)C4=C3)=NC=C2Cl)C=CC=C1)(C(C)C)=O
Molecular Formula
C26H32ClN5O3S
Molecular Weight
530.08
References & Citations
[1]Novel 2,4-diaminopyrimidines bearing fused tricyclic ring moiety for anaplastic lymphoma kinase (ALK) inhibitor
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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